Actively Recruiting
A Study Collecting Health Information to Understand and Prevent Gastric Cancer
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-01-30
3200
Participants Needed
7
Research Sites
626 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to create a registry of participants with precursor lesions for gastric cancer, including gastric atrophy, intestinal metaplasia, and dysplasia. Normal controls and individuals with gastric cancer for comparison of baseline characteristics will also be enrolled.
CONDITIONS
Official Title
A Study Collecting Health Information to Understand and Prevent Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Able to read and understand English or Spanish
- Diagnosed with gastric atrophy, intestinal metaplasia, or dysplasia confirmed by pathology or by the study team
- Individuals with prior early gastric cancer treated endoscopically and no current disease
- Individuals with prior cancer other than upper gastrointestinal cancer with no disease for at least 1 year and not undergoing active treatment
- Healthy controls with no history of cancer or gastric precursor lesions undergoing endoscopy for dyspepsia or reflux
- Individuals with early gastric adenocarcinoma undergoing surgical resection at MSK
You will not qualify if you...
- Younger than 18 years old
- Pregnant women (may join after delivery)
- History of upper gastrointestinal surgery or cancer under active treatment or diagnosed within 1 year prior to enrollment, or pancreatic cancer
- Severe health conditions with expected survival less than 2 years or preventing elective endoscopy
- Hereditary Diffuse Gastric Cancer Syndrome or multiple genetic mutations including CDH1 and CTNNA1
- High-risk esophageal or duodenal lesions such as duodenal adenoma or esophageal/gastroesophageal junction dysplasia or cancer
- Increased risk for biopsies during endoscopy, such as clotting disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Suffolk-Commack (Limited protocol activity)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All protocol activites)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau (Limited Protocol Activites)
Rockville Centre, New York, United States, 11553
Actively Recruiting
Research Team
M
Monika Laszkowska, MD
CONTACT
X
Xiang Shu, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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