Actively Recruiting
Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS
Led by Charles University, Czech Republic · Updated on 2026-03-19
592
Participants Needed
8
Research Sites
621 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Surgical correction of the prolapse in the anterior compartment remains one of the major challenges in urogynecology. Paravaginal defect in level II of vaginal fixation results in the majority of cystoceles. Clinically, these defects are often combined and/or may be bilateral. Hence, careful assessment and individualized planning of the surgical procedure is essential to optimize cystocele repair outcome. Several surgical techniques and approaches have been used for cystocele repair. After the ban on transvaginal meshes, the interest in native tissue repair has risen. Paravaginal defect repair is an effective surgery for paravaginal defect reconstruction. There is a current trend to utilize transvaginal surgery instead of more invasive transabdominal surgery. A novel method of transvaginal paravaginal defect repair - TOCR (transobturator cystocele repair) was suggested. The principle objective of the present trial is to compare its efficacy and safety to preexisting method of native tissue cystocele repair.
CONDITIONS
Official Title
Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 2nd stage prolapse of the anterior compartment (Ba 81)
- Age 50 years or older
- Symptom of bulge
- Ability to speak Czech or English
You will not qualify if you...
- Presence of malignancy
AI-Screening
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Trial Site Locations
Total: 8 locations
1
Faculty of Medicine in Hradec Kralove, Charles University
Hradec Králové, Czechia, 500 05
Not Yet Recruiting
2
Medical Faculty, Ostrava University
Ostrava-Poruba, Czechia, 708 52
Not Yet Recruiting
3
Hospital Pardubice Region, Inc.
Pardubice, Czechia, 530 03
Not Yet Recruiting
4
Faculty of Medicine in Pilsen, Charles University
Pilsen, Czechia, 30000
Actively Recruiting
5
Hospital na Bulovce, 1st Medical Faculty, Charles University
Prague, Czechia, 18000
Not Yet Recruiting
6
Tomas Bata Regional Hospital in Zlin
Zlín, Czechia, 762 75
Not Yet Recruiting
7
Košice Medical University
Košice, Slovakia, 040 11
Not Yet Recruiting
8
Trenčianska univerzita Alexandra Dubčeka
Trenčín, Slovakia, 911 01
Not Yet Recruiting
Research Team
V
Vladimir Kalis, prof. MD PhD
CONTACT
Z
Zdenek Rusavy, assoc. prof. MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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