Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT07547098

Study on Construction of Whole Lifecycle Cohort, Big Data Management and Clinical Prognosis of Cardio-Renal-Metabolic (CKM) Syndrome

Led by First Affiliated Hospital of Fujian Medical University · Updated on 2026-04-23

8000

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single-center observational registry study aiming to establish a structured clinical and multimodal imaging database for cardiovascular-kidney-metabolic (CKM) populations and to support lifecycle follow-up and outcome management. Adult patients aged 18-80 years with cardiovascular, kidney, and/or metabolic diseases or key data for CKM phenotyping will be enrolled at the First Affiliated Hospital of Fujian Medical University. The study integrates retrospective data entry and prospective follow-up, including clinical records, laboratory tests, medications, electrocardiography, echocardiography, vascular function assessment, carotid and abdominal ultrasound, bone density, coronary CTA and post-processing data. The primary outcome is the first occurrence of a cardiorenal composite endpoint. Participants will be followed for up to 5 years through active annual follow-up and passive monthly data updates to support risk stratification, real-world evidence generation, and CKM management pathway optimization.

CONDITIONS

Official Title

Study on Construction of Whole Lifecycle Cohort, Big Data Management and Clinical Prognosis of Cardio-Renal-Metabolic (CKM) Syndrome

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Inpatient record available at the First Affiliated Hospital of Fujian Medical University with retrievable identifiers for data linkage
  • Cardiovascular disease, kidney disease, metabolic disease, or key examination/laboratory information supporting CKM phenotyping
  • Willingness to participate and provision of written informed consent
  • Ability to complete baseline assessment and follow-up
  • Full civil capacity and ability to understand study information
Not Eligible

You will not qualify if you...

  • Refusal to provide written informed consent
  • Severe psychiatric disease or cognitive impairment precluding participation
  • End-stage disease with expected survival less than 1 year
  • Long-term absence more than 6 months preventing reliable follow-up
  • Participation in another clinical study that may interfere with endpoint adjudication
  • Missing key fields preventing linkage of examinations, imaging, and outcomes

AI-Screening

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China, 350011

Actively Recruiting

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Research Team

D

Dajun Chai

CONTACT

H

Hailin Zhang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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