Actively Recruiting
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
Led by Zhujiang Hospital · Updated on 2025-07-18
450
Participants Needed
1
Research Sites
234 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing. The enrolled patients underwent high-resolution magnetic resonance angiography to detect whether the intracranial aneurysm wall was enhanced and classify the degree of enhancement. The purpose is to study the correlation between arterial aneurysm wall enhancement and cotinine levels
CONDITIONS
Official Title
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-75 years old, male or infertile female
- Diagnosed with intracranial aneurysm through CTA, MRA, or DSA and suitable for endovascular intervention treatment
- Fully understand the research purpose and voluntarily agree to participate with signed consent
- Willing to undergo high-resolution magnetic resonance imaging
- Willing to follow up and be evaluated according to the clinical research protocol requirements
You will not qualify if you...
- Presence of arteriovenous malformation, Moyamoya disease, or dural arteriovenous fistula related aneurysms
- Contraindications to high-resolution magnetic resonance imaging
- Participation in other clinical trials involving drugs or medical devices
- Severe underlying diseases with very poor clinical condition unable to tolerate general anesthesia surgery
- Poor compliance or inability to cooperate with follow-up
- History or suspicion of severe allergy to contrast agents
- Life expectancy less than 2 years
- Women who are breastfeeding or planning pregnancy during the study period
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhujiang Hospital, Southern Medical University
Guangzhou, Guangdong, China, 528400
Actively Recruiting
Research Team
X
Xin Feng, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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