Actively Recruiting
A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation
Led by Ru-zhou Cai · Updated on 2025-09-18
700
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the connection between portal vein thrombosis (PVT) and outcomes after liver transplantation. The study aims to find out how common PVT is, what risk factors contribute to it, and how having PVT before surgery affects the prognosis of liver transplant patients. The goal also includes developing a new grading or rating system for PVT to improve clinical care. Participants are grouped into those with PVT and those without PVT before their liver transplant. The study does not involve any treatment or intervention but observes and compares data from both groups. Medical imaging, surgical details, pathology reports, treatments after surgery, and follow-up information will be collected and analyzed to understand PVT’s impact. During the study, researchers will gather demographic and laboratory data, imaging results, and clinical outcomes over time. The main outcomes measured include death, postoperative PVT, and portal vein narrowing over a 10-year period, along with complications within 1 year after surgery. The study monitors participants through their clinical records to build predictive models and clarify how PVT influences transplant prognosis.
CONDITIONS
Brief Title
A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Liver transplantation recipients
- Aged 18 years or older
You will not qualify if you...
- Retransplantation
- Multi-organ transplantation
- Portal vein tumor thrombus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 week
Participants undergo preoperative imaging such as ultrasound and/or computed tomography to determine the presence or absence of portal vein thrombosis before liver transplantation.
1 to 2 visits depending on imaging schedule
Duration - Up to 10 years
Participants who undergo routine liver transplantation are observed to collect data on perioperative medical imaging, surgical procedures, pathology reports, postoperative treatments, and clinical outcomes.
Follow-up visits according to clinical care over 10 years
Trial Site Locations
Total: 1 location
1
Beijing Friendship Hospital, Capital Medical University
Beijing, China
Actively Recruiting
Research Team
R
Ru-zhou Cai, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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