Actively Recruiting
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants
Led by Hoffmann-La Roche · Updated on 2026-04-15
128
Participants Needed
1
Research Sites
62 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this study is to evaluate the safety and tolerability of single and multiple ascending doses of RO7806881 in healthy participants.
CONDITIONS
Official Title
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males or females who are overtly healthy based on medical evaluation
- Body weight of at least 40 kilograms
- Body mass index (BMI) between 18 and 32 kilograms per square meter (inclusive)
You will not qualify if you...
- Pregnancy, breastfeeding, or planning pregnancy during the study or within 6 months after the last dose
- History of significant autoimmune, gastrointestinal, kidney, liver, lung, neurological, psychiatric, heart, endocrine, blood, allergic diseases, metabolic disorders, cancer, or cirrhosis
- Latent or active tuberculosis
- Major illness within 1 month before screening or fever within 1 week before screening and dosing
- Any condition or treatment that could interfere with the study or pose unacceptable risk
- History of allergic reactions to biologic agents or study drug components
- Live vaccines within 1 month before screening or during screening
- Non-live vaccines within 2 weeks before dosing
- Previous exposure to RO7806881
- Positive tests for hepatitis C, hepatitis B, HIV, cytomegalovirus, or Epstein-Barr virus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
New Zealand Clinical Research - Christchurch
Christchurch, New Zealand, 8011
Actively Recruiting
Research Team
R
Reference Study ID Number: BP46089 https://forpatients.roche.com/
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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