Study of Perioperative Energy Use and Its Link to Recovery After Surgery in Adults with Esophageal and Lung Cancer

What this Trial Is About

This research aims to validate a new method for assessing perioperative risk in patients with esophageal and lung cancer undergoing major cancer surgery. It focuses on understanding how neoadjuvant therapies such as chemotherapy, radiation therapy, and immunotherapy impact patients functional capacity as measured by gas exchange parameters before and after these treatments. The study also explores whether postoperative complications are related to perioperative cardiopulmonary gas exchange and metabolism. Participants will undergo cardiopulmonary exercise testing CPET, which involves pedaling on a stationary bicycle at 60 revolutions per minute with gradually increasing resistance. The testing is done before and after neoadjuvant therapy, and after surgery, to measure changes in functional capacity. This observational study tracks these changes and their correlation with postoperative outcomes over time. During the study, participants will be monitored for perioperative risk with assessments at baseline and up to 30 days after surgery to identify any morbid events. Researchers will collect data from CPET measures and other diagnostic evaluations completed as part of routine care. The study involves evaluations by anesthesiology staff and requires completion of all necessary laboratory and diagnostic tests. Total participation duration varies depending on treatment timelines and surgery schedules.

A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes