Actively Recruiting

Phase 2
Age: 18Years - 65Years
All Genders
NCT04899687

Study of Dextromethorphan in OCD and Related Disorders

Led by Stanford University · Updated on 2025-08-27

60

Participants Needed

1

Research Sites

253 weeks

Total Duration

On this page

Sponsors

S

Stanford University

Lead Sponsor

A

Avy L. & Roberta L. Miller Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.

CONDITIONS

Official Title

Study of Dextromethorphan in OCD and Related Disorders

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), illness anxiety disorder (IAD) or somatic symptom disorder (SSD)
  • Living within California
  • Capacity to provide informed consent
Not Eligible

You will not qualify if you...

  • Current bipolar disorder or psychotic disorder
  • Active moderate or severe substance use disorder, lifetime severe substance use disorder
  • Pregnant or nursing women
  • Use of prescribed psychotropic medications other than fluoxetine for 2 weeks prior to study start
  • Having commenced OCD-targeted exposure and response-prevention (ExRP) psychotherapy within 2 months of study start

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stanford University

Stanford, California, United States, 94304

Actively Recruiting

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Research Team

P

Pavithra Mukunda, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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Study of Dextromethorphan in OCD and Related Disorders | DecenTrialz