Actively Recruiting

Phase 1
Age: 18Years - 49Years
All Genders
Healthy Volunteers
NCT07516418

Study of Different Formulations of Vaccines Encoding the RSV Monovalent Antigen or the Flu H5 Antigen in Participants 18 to 49 Years of Age

Led by Sanofi · Updated on 2026-05-08

570

Participants Needed

6

Research Sites

50 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the safety and immunogenicity of different formulations of vaccines encoding the RSV monovalent antigen or the Flu hemagglutinin subtype 5 (H5) antigen in healthy participants aged 18 to 49 years. The total duration of study participation for each participant varies by stage and treatment arm. Stage 1: * For Arm 1, Arm 2, and Arm 3 the duration of study participation will be approximately 7 months for each participant. * For Arm 4, Arm 5, and Arm 6 the duration of study participation will be approximately 6 months for each participant. Stage 2: For all arms, the duration of study participation will be approximately 7 months for each participant.

CONDITIONS

Official Title

Study of Different Formulations of Vaccines Encoding the RSV Monovalent Antigen or the Flu H5 Antigen in Participants 18 to 49 Years of Age

Who Can Participate

Age: 18Years - 49Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 to 49 years on the day of inclusion
  • Female participants must not be pregnant or breastfeeding
  • Females who are not of child-bearing potential must be post-menopausal for at least 1 year or surgically sterile
  • Females of child-bearing potential must use effective contraception or abstinence from 4 weeks before until 12 weeks after last study intervention
Not Eligible

You will not qualify if you...

  • Any condition that might interfere with the evaluation of the study objectives as determined by the Investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

Site # 0361002

Griffith, Queensland, Australia, 4222

Actively Recruiting

2

Site # 0361001

Herston, Queensland, Australia, 4006

Actively Recruiting

3

Site # 0361003

Morayfield, Queensland, Australia, 4506

Actively Recruiting

4

Site # 0361005

Sippy Downs, Queensland, Australia, 4556

Actively Recruiting

5

Site # 03610004

South Brisbane, Queensland, Australia, 4104

Actively Recruiting

6

Site # 036006

Taringa, Queensland, Australia, 4068

Actively Recruiting

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Research Team

S

Sanofi Trial Transparency Email Recommended (Toll free for US and Canada)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

PREVENTION

Number of Arms

12

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Study of Different Formulations of Vaccines Encoding the RSV Monovalent Antigen or the Flu H5 Antigen in Participants 18 to 49 Years of Age | DecenTrialz