Actively Recruiting
Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.
Led by The Institute of Molecular and Translational Medicine, Czech Republic · Updated on 2026-02-12
3200
Participants Needed
3
Research Sites
391 weeks
Total Duration
On this page
Sponsors
T
The Institute of Molecular and Translational Medicine, Czech Republic
Lead Sponsor
C
Cancer Research Foundation CR
Collaborating Sponsor
AI-Summary
What this Trial Is About
The trial will evaluate if the newly identified biomarkers of lung cancer in exhaled breath condensate are as a diagnostic tool comparable to the low-dose computer tomography (LDCT) implemented in lung cancer screening recently. Due to the possibility to collect breath condensate at any medical workplace and due to the relatively low financial cost of examination of the collected breath condensate could improve early diagnosis of lung cancer, differential diagnostics of lung nodules and thereby reduce both the unnecessary interventions and deaths from this type of cancer.
CONDITIONS
Official Title
Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Consent to participate in the clinical trial
- Age between 55 and 74 years
- Current smoker or ex-smoker with at least 20 pack-years of smoking history
- Priority given to those with at least 30 pack-years of smoking
- Preference for former smokers who quit less than 15 years ago
You will not qualify if you...
- Previous diagnosis of lung cancer
- Ongoing symptomatic treatment for active malignant tumor
- Advanced dementia
- Chronic obstructive pulmonary disease or other inflammatory lung disease in acute exacerbation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Masaryk Memorial Cancer Institute
Brno, Czechia, 65653
Actively Recruiting
2
University Hospital
Olomouc, Czechia, 77900
Not Yet Recruiting
3
General University Hospital in Prague
Prague, Czechia, 12808
Not Yet Recruiting
Research Team
M
Marian Hajduch, MD, PhD.
CONTACT
M
Michaela Bendova, MSc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here