Effects of Capsinoid Supplements on Brown Fat Activity in Obese Adolescents Aged 11 to 18 Years

What this Trial Is About

Researchers are investigating the effects of capsinoid dietary supplements on brown adipose tissue BAT activity in obese adolescents aged 11 to 18 years. BAT is a special type of fat that helps regulate energy use by producing heat, which may help reduce obesity. This study aims to see if capsinoid supplements combined with dietary management can increase BAT activity in this group. Participants will be randomly assigned to one of two groups. One group will receive capsules containing capsinoids, a compound found in sweet peppers and chillies, taken three times daily for four weeks. The control group will receive similar capsules without the active ingredient. Both groups will participate in a four-week multidimensional care program during the study. Throughout the study, researchers will measure changes in BAT activity using temperature differences in specific body regions before and after cold exposure. Other assessments include blood flow, metabolism, heart rate patterns, blood sugar and lipid profiles, hormone levels, body measurements, eating behavior, and pubertal development. Treatment adherence will be monitored continuously during the program, with evaluations at the start and end of the four weeks.

Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents