Actively Recruiting
A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-16
216
Participants Needed
8
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find the level of aerobic exercise (AT) that is practical, is safe, and has positive effects on the body that may reduce the side effects of therapy. The study will also look at the way the body responds to exercise and whether there are differences in treatment. This will include looking at the highest treatment dose participants receive, how many people stop, delay, or reduce the treatment, and whether additional medication is needed to treat side effects of therapy.
CONDITIONS
Official Title
A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Diagnosed with colorectal or esophago/gastric solid tumors confirmed by histology or standard imaging
- Scheduled for neoadjuvant chemotherapy or chemotherapy for newly diagnosed metastatic disease
- Performing 90 minutes or less of structured moderate or strenuous exercise per week by self-report
- Willing to follow all study procedures
- Cleared for exercise participation by Physical Activity Readiness Questionnaire screening
You will not qualify if you...
- Enrolled in any other lifestyle interventional investigational study, except those not expected to affect study outcomes
- Receiving treatment for any other invasive cancer diagnosis
- Having mental impairment preventing cooperation
- Having any other condition or illness judged by the investigator as making participation unsafe or unsuitable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
Hartford Healthcare Alliance (Data Collection Only)
Hartford, Connecticut, United States, 06102
Actively Recruiting
2
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
3
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, United States, 07748
Actively Recruiting
4
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, United States, 07645
Actively Recruiting
5
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
Commack, New York, United States, 11725
Actively Recruiting
6
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, United States, 10604
Actively Recruiting
7
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
8
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Rockville Centre, New York, United States, 11553
Actively Recruiting
Research Team
J
Jessica Scott, PhD
CONTACT
A
Andrea Cercek, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here