Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05888428

Study of Efficacy of the MyoTrain System in a Population of Individuals With Trans-radial Limb Loss

Led by Infinite Biomedical Technologies · Updated on 2025-10-29

16

Participants Needed

1

Research Sites

134 weeks

Total Duration

On this page

Sponsors

I

Infinite Biomedical Technologies

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators propose to evaluate the efficacy of MyoTrain in a prospective clinical study involving 16 individuals with trans-radial upper-limb loss over a period of 206 days. These individuals will be randomized to Group A (Control Group using standard motor imagery training) and Group B (who are provided the MyoTrain system). The investigators will test three hypotheses: 1. The use of MyoTrain results in skills transference to control of the final prosthesis 2. The virtual outcome measures in MyoTrain are correlated with real-world functional outcome measures 3. The use of MyoTrain results in improved clinical outcomes as measured by functional, subjective and usage metrics Following a baseline functional assessment, participants will undergo a 30-day pre-prosthetic training period specific to their assigned Group. After this training period, participants will receive their prosthetic device and occupational therapy consistent with the current clinical care standard, after which they will again undergo clinical assessment. Post-device delivery, participants will then complete 3 56-day blocks of at-home prosthesis use, in between which they will return to clinic for assessment.

CONDITIONS

Official Title

Study of Efficacy of the MyoTrain System in a Population of Individuals With Trans-radial Limb Loss

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Trans-radial unilateral limb loss
  • Candidate for a 2+ degree-of-freedom myoelectric pattern recognition prosthesis as determined by prosthetist
  • Fluent in English
  • Age of 18 years or greater
Not Eligible

You will not qualify if you...

  • Prior experience with pattern recognition control
  • Residual limb unhealed from amputation surgery
  • Easily damaged or sensitive skin intolerant to EMG electrodes
  • Unhealed wounds
  • Significant cognitive deficits as determined by clinical evaluation
  • Significant neurological deficits as determined by clinical evaluation
  • Significant physical deficits of the residual limb impacting study participation
  • Uncontrolled pain or phantom pain impacting study participation
  • Serious uncontrolled medical problems judged by the project therapist

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Hanger Clinic - Grand Rapids

Grand Rapids, Michigan, United States, 49546

Actively Recruiting

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Research Team

R

Rahul R Kaliki

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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