Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT04278339

Study of Electrophysiological Markers Related to the Cognitive and Affective Processes Behind Empathic Behaviour in Schizophrenic Spectrum Disorder

Led by Centre Hospitalier Universitaire de Nice · Updated on 2025-03-24

70

Participants Needed

1

Research Sites

311 weeks

Total Duration

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AI-Summary

What this Trial Is About

Disorders of social cognition, and empathy more specifically, are at the heart of schizophrenic pathology in that they are strongly linked to the social handicap of patients. It is therefore necessary to refine our knowledge of the cognitive and affective processes behind this empathic disorder and to identify objective and easily measurable markers (related to brain functioning collected by electroencephalography) of these processes with the subsequent aim of improving their management. It is also relevant to question the trait/status nature of these empathic disorders by studying these markers in individuals presenting more or less marked schizotypic traits and therefore more or less at risk of developing schizophrenia. Studying the possibility that empathy disorders may be part of the factors of developmental vulnerability for schizophrenia and identifying objective markers of this vulnerability could allow, in case of development of the pathology, a more rapid diagnosis and a more effective management.

CONDITIONS

Official Title

Study of Electrophysiological Markers Related to the Cognitive and Affective Processes Behind Empathic Behaviour in Schizophrenic Spectrum Disorder

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Good command of the French language
  • Right-handed
  • Diagnosis of schizophrenia or schizoaffective disorder
  • Clinical state stabilized according to the treating psychiatrist
Not Eligible

You will not qualify if you...

  • History of head injury with loss of consciousness lasting more than 5 minutes
  • Participating in another project at the time of this study
  • Addiction to toxic substances (excluding tobacco)
  • Mental retardation or neurological disorder
  • Significant change in treatment in the previous month (patients only)
  • Currently hospitalized (patients only)
  • Taking psychoactive drugs (controls only)
  • Having a mental disorder (controls only)
  • First-degree relative of a patient with a disorder other than schizophrenia or schizoaffective disorder (controls only)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Hôpital Pasteur - Service de Psychiatrie

Nice, France, 06001

Actively Recruiting

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Research Team

B

Bruno GIORDANA, PH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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