Actively Recruiting
Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder
Led by Centre Hospitalier Universitaire de Besancon · Updated on 2025-07-22
80
Participants Needed
3
Research Sites
70 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier Universitaire de Besancon
Lead Sponsor
I
INSERM UMR 1322 LINC
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this exploratory, interventional, multicentre study is to compare the prefrontal activity during a negative emotion regulation task in women with Binge-Eating Disorder (BED) and healthy women with and without Emotional Eating (EE). The aim of this study is to compare the prefrontal processing of cognitive control of emotions between BED and EE and to compare the emotional processing and emotional experience between BED and EE. The study will thus compare four experimental groups: patients with BED, BMI-matched healthy volunteers with EE, BMI-matched healthy volunteers, and healthy volunteers of normal weight without BED. Participants will perform a down-regulation task of negative emotions elicited by negative pictures. During this task, their cerebral activity will be recorded using functional near-infrared spectroscopy (fNIRS), as well as their autonomous activity (skin conductance, pulse rate, respiration rate).
CONDITIONS
Official Title
Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women between 18 and 60 years old (including 60)
- Right-handed
- For patients only: diagnosed with Binge Eating Disorder according to DSM criteria
- Membership of a French social security scheme or beneficiary of such a scheme
- Non-opposition to participate in the study
You will not qualify if you...
- Healthy volunteers with any eating disorder or other psychiatric disorder
- History of bariatric surgery
- Rare obesity (genetic or syndromic)
- Specific addictions (substances or behaviors)
- Neurological disorders or history of stroke or head trauma
- Lesions, wounds, or dermatitis at recording device sites
- Serious acute or chronic illness other than the study condition
- Treatment interfering with study evaluation
- Inability to follow protocol requirements
- Poor cooperation anticipated by investigator
- Unable to speak French or read
- Pregnant or breastfeeding women
- Persons deprived of liberty by judicial or administrative decision
- Persons under compulsory psychiatric care
- Persons admitted to a health or social institution for purposes other than research
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 3 locations
1
UFC - UFR Santé
Besançon, France, 25000
Actively Recruiting
2
CHU de Besançon
Besançon, France, 25030
Not Yet Recruiting
3
CHU de Dijon
Dijon, France, 21000
Actively Recruiting
Research Team
B
BILLOT Pierre-Edouard, PhD
CONTACT
P
POZET Astrid
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
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