Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06614101

Study Enabling the Collection of Clinical Data Necessary for the Second Phase of Development of the Glycemic Measurement Device by Analysis of Exhaled Air

Led by University Hospital, Toulouse · Updated on 2024-10-24

235

Participants Needed

2

Research Sites

85 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A pilot study carried out by the company ALPHA-MOS in 2017-19 showed that the analysis of volatile organic compounds contained in exhaled air could reliably predict blood glucose levels. Subsequently, the company BOYDSense, a subsidiary of ALPHA-MOS, produced the Module In a Box prototypes of portable, non-invasive volatile organic compounds analyzers that could be equipped with an on-board algorithm estimating blood glucose levels. The Toulouse University Hospital conducted the BOYDSENSE-GM study in 2021-2023, in partnership with BOYDSense, aiming to develop the first algorithm for calculating blood glucose levels based on the analysis of the breath of 100 patients living with type 2 diabetes and to carry out a first performance test of the Module In a Box prototype in 30 additional subjects with type 2 diabetes. These recent results confirmed the potential of this innovative blood glucose measurement technology and gave the first indications about the next developments needed to improve its performances. The characteristics of the air exhaled by a human are impossible to simulate. Therefore, further development of the glucose calculation algorithm requires the production of additional clinical data, supporting the carrying out of the present study.

CONDITIONS

Official Title

Study Enabling the Collection of Clinical Data Necessary for the Second Phase of Development of the Glycemic Measurement Device by Analysis of Exhaled Air

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient living with type 2 diabetes or non-diabetic individuals with overweight or obesity (BMI ≥ 25 Kg/m²), admitted to Toulouse University Hospital departments of Diabetology, Metabolic Diseases and Nutrition or Endocrinology, Metabolic Diseases and Nutrition
  • Aged 18 years or older
  • Able to sign informed consent
  • Affiliated to a social security scheme
Not Eligible

You will not qualify if you...

  • Ongoing respiratory infection
  • Pregnancy or breastfeeding
  • Under guardianship, curatorship, or safeguard of justice

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Fontaine Salée Hospital

Salies-du-Salat, France, France, 31 260

Not Yet Recruiting

2

Rangueil Hospital

Toulouse, France, France, 31059

Actively Recruiting

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Research Team

P

Pierre Gourdy, MD

CONTACT

L

Laurent Cazals

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Study Enabling the Collection of Clinical Data Necessary for the Second Phase of Development of the Glycemic Measurement Device by Analysis of Exhaled Air | DecenTrialz