Actively Recruiting
Study of an Environmental Risk Factor in Crohn's Disease
Led by University Hospital, Lille · Updated on 2025-12-26
100
Participants Needed
1
Research Sites
248 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Lille
Lead Sponsor
N
National Research Agency, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
Inflammatory bowel disease (IBD) are lifelong chronic diseases affecting the gastrointestinal tract. The precise etiology and the different actors participating to the pathophysiological process leading to the disease development are still not well understood. A complex interaction between genetics, gut microbiota and environmental factors is thought to trigger the inappropriate mucosal immune response observed in IBD patients. We hypothesize that DON might be an environmental risk factor for IBD.The focus on the human relevance of the gut effects of DON by studying its exposure, metabolism and adverse effects in health and disease focusing on IBD patients
CONDITIONS
Official Title
Study of an Environmental Risk Factor in Crohn's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with ileocolic Crohn's disease requiring surgery
- Patients requiring ileal or colonic surgery for reasons other than Crohn's disease or ulcerative colitis (e.g., cancer, polyp, diverticulum)
You will not qualify if you...
- Vegetarian or vegan patients
- Patients with celiac disease or gluten sensitivity
- Patients with eating disorders or particular diets, including obesity or anorexia
- Patients who have had previous intestinal surgery
- Patients treated with antibiotics or probiotics within 6 weeks prior to inclusion
- Patients who have used topical treatments (5ASA or corticosteroids suppositories or enemas) within 6 weeks prior to inclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lille University Hospital
Lille, France
Actively Recruiting
Research Team
P
Philippe ZERBIB, MD,PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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