Actively Recruiting

Phase 1
Age: 18Years - 30Years
All Genders
Healthy Volunteers
NCT07478952

A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18 to 30 Years of Age

Led by ModernaTX, Inc. · Updated on 2026-03-24

120

Participants Needed

2

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main objective of this trial is to evaluate the safety and immunogenicity of mRNA-1189 after intradermal and intramuscular delivery.

CONDITIONS

Official Title

A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18 to 30 Years of Age

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy as determined by medical evaluation including medical history and physical examination.
  • Participants who are assigned female at birth or could become pregnant are eligible to participate if the participant is not pregnant or breast/chest feeding.
Not Eligible

You will not qualify if you...

  • Have undergone surgical procedures within 7 days prior to Day 1 or Day 57 or are scheduled to undergo a surgical procedure within 28 days after study intervention administration.
  • Reported history of congenital or acquired immunodeficiency, immunosuppressive condition, asplenia, or recurrent severe infectious disease.
  • Received corticosteroids at ≥10 milligrams per day (mg/day) of prednisone or equivalent for >14 days in total within 90 days prior to Day 1 or is anticipating the need for corticosteroids at any time during the study.
  • Received systemic immunosuppressive treatment, including long-acting biological therapies that affect immune responses, within 180 days prior to Day 1 or plans to do so during the study.
  • Received or plans to receive any nonstudy vaccine from 28 days prior to first dose/Day 1 up to 28 days after the second dose/Day 57.
  • History of myocarditis, pericarditis, or myopericarditis prior to Day 1.
  • Has previously received an investigational EBV vaccine.

Note: Other inclusion and exclusion criteria may apply.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Nucleus Network

Melbourne, Victoria, Australia, VIC 3004

Actively Recruiting

2

Doherty Clinical Trials

Melbourne, Victoria, Australia, VIC 3149

Not Yet Recruiting

Loading map...

Research Team

M

Moderna WeCare Team

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here