Actively Recruiting
A Study to Evaluate the Effect of KarXT on Urological Safety
Led by Bristol-Myers Squibb · Updated on 2026-04-30
60
Participants Needed
14
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to characterize the effect of KarXT on voiding dynamics and urological safety in participants with DSM-5 schizophrenia.
CONDITIONS
Official Title
A Study to Evaluate the Effect of KarXT on Urological Safety
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female participants aged 18 to 65 years
- Primary diagnosis of schizophrenia based on psychiatric evaluation (DSM-5) and confirmed by MINI (v 7.0.2)
- PANSS total score of 80 or less and CGI-S score of 4 or less at screening and baseline
- Body mass index (BMI) between 18 and 40 kg/m2
- Willing and able to discontinue all antipsychotic medications prior to baseline visit
- Willing and able to comply with protocol requirements
You will not qualify if you...
- Newly diagnosed schizophrenia or any other DSM-5 disorder diagnosed within the past 12 months
- Alcohol or drug use disorder within the past 12 months
- History or presence of any clinically significant disease or disorder that could affect safety or study results
- At risk for suicidal behavior
- Pregnant or breastfeeding individuals
- Other protocol-defined inclusion or exclusion criteria apply
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
Pillar Clinical Research- Little Rock
Little Rock, Arkansas, United States, 72204
Actively Recruiting
2
Clinical Innovations, Inc. dba CITrials
Bellflower, California, United States, 90706
Actively Recruiting
3
Local Institution - 0009
Culver City, California, United States, 90230
Not Yet Recruiting
4
CenExel CNS - Garden Grove
Garden Grove, California, United States, 92845
Actively Recruiting
5
ATP Clinical Research
Orange, California, United States, 92866
Actively Recruiting
6
Local Institution - 0003
Miami, Florida, United States, 33016
Not Yet Recruiting
7
Local Institution - 0004
West Palm Beach, Florida, United States, 33407
Not Yet Recruiting
8
Uptown Research Institute
Chicago, Illinois, United States, 60640
Actively Recruiting
9
Local Institution - 0010
Chicago, Illinois, United States, 60641
Not Yet Recruiting
10
IMA Clinical Research Las Vegas
Las Vegas, Nevada, United States, 89102
Actively Recruiting
11
Hassman Research Institute Marlton Site
Marlton, New Jersey, United States, 08053
Actively Recruiting
12
Adams Clinical Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
13
Local Institution - 0001
Austin, Texas, United States, 78754
Not Yet Recruiting
14
InSite Clinical Research
DeSoto, Texas, United States, 75115
Actively Recruiting
Research Team
B
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
CONTACT
F
First line of the email MUST contain NCT # and Site #.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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