Actively Recruiting
A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia in an Older Adult Population Aged 76 Years or Older in Finland
Led by GlaxoSmithKline · Updated on 2026-05-12
33609
Participants Needed
8
Research Sites
574 weeks
Total Duration
On this page
Sponsors
G
GlaxoSmithKline
Lead Sponsor
F
Finnish Vaccine Research;
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the effect of the recombinant zoster vaccine on the risk of new diagnosis of dementia among adults aged 76 years or older in Finland. Participants will be enrolled and randomized in a 3:1 ratio to receive either recombinant zoster vaccine or placebo.
CONDITIONS
Official Title
A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia in an Older Adult Population Aged 76 Years or Older in Finland
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Citizens living permanently in Finland who can and will comply with the study requirements
- Written or witnessed informed consent obtained before any study procedures
- Age 76 years or older at the time of signing informed consent
You will not qualify if you...
- Prior receipt of a Herpes Zoster vaccine
- History of dementia diagnosis before enrollment, including confirmed cases or ongoing investigations
- Use of dementia treatment medications prior to enrollment
- Current or recent cognitive assessments for memory deficits or suspected dementia that are ongoing or inconclusive
- Severe immunocompromise
- Participation in another clinical trial involving investigational products or dementia prevention
- Known severe allergic reactions to vaccine components or similar vaccines
- Living in a nursing facility
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
GSK Investigational Site
Espoo, Finland, 02230
Actively Recruiting
2
GSK Investigational Site
Helsinki, Finland, 00100
Actively Recruiting
3
GSK Investigational Site
Jarvenpaa, Finland, 04400
Actively Recruiting
4
GSK Investigational Site
Kokkola, Finland, 67100
Actively Recruiting
5
GSK Investigational Site
Oulu, Finland, 90220
Actively Recruiting
6
GSK Investigational Site
Seinäjoki, Finland, 60100
Actively Recruiting
7
GSK Investigational Site
Tampere, Finland, 33100
Actively Recruiting
8
GSK Investigational Site
Turku, Finland, 20520
Actively Recruiting
Research Team
U
US GSK Clinical Trials Call Center
CONTACT
E
EU GSK Clinical Trials Call Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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