Actively Recruiting
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
Led by Bristol-Myers Squibb · Updated on 2026-04-28
194
Participants Needed
33
Research Sites
587 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the effectiveness, safety, tolerability, drug levels and drug effects of ozanimod compared to fingolimod in children and adolescents with relapsing remitting multiple sclerosis (RRMS).
CONDITIONS
Official Title
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of multiple sclerosis with a relapsing remitting course as per 2017 McDonald Criteria
- At least 1 MS relapse in the previous year or at least 2 relapses in the previous 2 years
- Evidence of one or more gadolinium-enhancing lesions on MRI within 6 months prior to baseline
- Expanded Disability Status Scale (EDSS) score from 0 to 5.5 inclusive
You will not qualify if you...
- Diagnosis of progressive forms of multiple sclerosis
- Active or chronic immune system disease other than multiple sclerosis
- Clinically relevant cardiovascular, liver, neurological, or other major systemic disease
- Other protocol-defined inclusion or exclusion criteria apply
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 33 locations
1
Local Institution - 0114
Loma Linda, California, United States, 92354
Not Yet Recruiting
2
University of California Davis Health
Sacramento, California, United States, 95817
Actively Recruiting
3
University of South Florida
Tampa, Florida, United States, 33612
Actively Recruiting
4
Local Institution - 0093
Chicago, Illinois, United States, 60611
Withdrawn
5
University of Chicago Medical Center
Chicago, Illinois, United States, 60637
Actively Recruiting
6
University of Louisville, Norton Children's Research Institute
Louisville, Kentucky, United States, 40202
Actively Recruiting
7
Local Institution - 0131
New Brunswick, New Jersey, United States, 08901
Not Yet Recruiting
8
Local Institution - 0132
Teaneck, New Jersey, United States, 07666
Withdrawn
9
Local Institution - 0091
Cincinnati, Ohio, United States, 45229
Withdrawn
10
Local Institution - 0092
Portland, Oregon, United States, 97225
Not Yet Recruiting
11
Local Institution - 0133
El Paso, Texas, United States, 79912
Not Yet Recruiting
12
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
13
Royal Children's Hospital
Melbourne, Victoria, Australia, 3052
Actively Recruiting
14
University of Naples Federico II
Naples, Campania, Italy, 80131
Actively Recruiting
15
Ospedale San Raffaele
Milan, Lombardy, Italy, 20132
Actively Recruiting
16
Local Institution - 0081
Milan, Lombardy, Italy, 20133
Not Yet Recruiting
17
Neurological Center Of Latium
Rome, Roma, Italy, 00178
Actively Recruiting
18
Local Institution - 0078
Mexico City, DIF, Mexico, 04530
Withdrawn
19
Uniwersytecki Szpital Kliniczny w Poznaniu
Poznan, Greater Poland Voivodeship, Poland, 60-355
Actively Recruiting
20
2Ca Braga
Braga, Portugal, 4710-243
Actively Recruiting
21
Unidade Local de Saúde de Coimbra, E.P.E.
Coimbra, Portugal, 3000-602
Actively Recruiting
22
Centro Hospitalar de Lisboa Central
Lisbon, Portugal, 1169-050
Actively Recruiting
23
Local Institution - 0102
Porto, Portugal, 4200-319
Withdrawn
24
Local Institution - 0134
Caguas, Puerto Rico, 00725
Not Yet Recruiting
25
Spitalul Clinic de Copii Doctor Victor Gomoiu
Bucharest, Bucharest, Romania, 022102
Actively Recruiting
26
Prof. Dr. Alexandru Obregia Psychiatry Hospital
Bucharest, Bucharest, Romania, 041914
Actively Recruiting
27
Local Institution - 0096
Esplugues de Llobregat, Barcelona [Barcelona], Spain, 08950
Not Yet Recruiting
28
CHUVI- Hospital Alvaro Cunqueiro
Vigo, Pontevedra [Pontevedra], Spain, 36203
Actively Recruiting
29
Hospital Universitario Virgen Macarena
Seville, Spain, 41009
Actively Recruiting
30
Hospital Universitari i Politecnic La Fe
Valencia, Spain, 46026
Actively Recruiting
31
Hospital Universitario Miguel Servet
Zaragoza, Spain, 50009
Actively Recruiting
32
National Taiwan University Hospital
Taipei, Taiwan, 10002
Actively Recruiting
33
Ondokuz Mayıs Universitesi
Samsun, Turkey (Türkiye), 55270
Actively Recruiting
Research Team
B
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
CONTACT
F
First line of the email MUST contain NCT # and Site #.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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