Actively Recruiting
A Study to Evaluate Effectiveness and Safety of a TYK2 Inhibitor in Subjects With Moderate to Severe Plaque Psoriasis
Led by Usynova Pharmaceuticals Ltd. · Updated on 2025-11-18
140
Participants Needed
1
Research Sites
31 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A Study to evaluate efficacy and safety in subjects with moderate to severe Plaque Psoriasis treated with a TYK2 Inhibitor for 12 weeks
CONDITIONS
Official Title
A Study to Evaluate Effectiveness and Safety of a TYK2 Inhibitor in Subjects With Moderate to Severe Plaque Psoriasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female, ages 18 to 70 years
- Body weight greater than 40 kg and body mass index (BMI) between 18 and 40 kg/m2
- Clinical diagnosis of plaque psoriasis for at least 6 months before the Baseline visit
- Women of childbearing potential and sexually active males must agree to use contraception methods
You will not qualify if you...
- Diagnosed with non-plaque psoriasis
- Previously received tyrosine kinase 2 (TYK2) inhibitors
- Previously received other psoriasis treatments such as biological agents, immunoregulators, or hormonal drugs within a specific period before administration if it may affect immunity
- Participated in any clinical trials within 30 days or 5 half-lives of the drug before first administration, or currently in other clinical trials
- History of chronic diseases affecting the study or acute or chronic severe infections, including active or untreated latent tuberculosis and severe bone or joint infections within 6 months before screening
- Known or suspected skin or systemic autoimmune diseases other than psoriasis and psoriatic arthritis
- Other conditions deemed unsuitable by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Skin Disease Hospital
Shanghai, China
Actively Recruiting
Research Team
Y
Yang Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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