Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT07105111

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

Led by Neurocrine Biosciences · Updated on 2026-05-08

50

Participants Needed

21

Research Sites

70 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will evaluate the efficacy of valbenazine on clinician- and patient-reported outcomes in participants with TD while receiving or after stopping a VMAT2 inhibitor.

CONDITIONS

Official Title

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Diagnosed with schizophrenia, schizoaffective disorder, bipolar disorder, or major depressive disorder at least 3 months before screening
  • Diagnosed with at least mild neuroleptic-induced tardive dyskinesia for at least 3 months before screening
Not Eligible

You will not qualify if you...

  • Presence of Parkinsonism or abnormal involuntary movements more prominent than tardive dyskinesia
  • Diagnosis of moderate or severe substance use disorder within the last 6 months
  • History of long QT syndrome, cardiac arrhythmia, or severe liver impairment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 21 locations

1

Neurocrine Clinical Site

Bryant, Arkansas, United States, 72022

Actively Recruiting

2

Neurocrine Clinical Site

Chino, California, United States, 91710

Actively Recruiting

3

Neurocrine Clinical Site

Fountain Valley, California, United States, 92708

Actively Recruiting

4

Neurocrine Clinical Site

Fresno, California, United States, 93720

Actively Recruiting

5

Neurocrine Clinical Site

Long Beach, California, United States, 90807

Actively Recruiting

6

Neurocrine Clinical Site

Orange, California, United States, 92866

Actively Recruiting

7

Neurocrine Clinical Site

Redlands, California, United States, 92373

Actively Recruiting

8

Neurocrine Clinical Site

San Diego, California, United States, 92123

Actively Recruiting

9

Neurocrine Clinical Site

Bonita Springs, Florida, United States, 34134

Actively Recruiting

10

Neurocrine Clinical Site

Hialeah, Florida, United States, 33012

Actively Recruiting

11

Neurocrine Clinical Site

Miami, Florida, United States, 33144

Actively Recruiting

12

Neurocrine Clinical Site

Miami, Florida, United States, 33176

Actively Recruiting

13

Neurocrine Clinical Site

Orange City, Florida, United States, 32763

Actively Recruiting

14

Neurocrine Clinical Site

Port Charlotte, Florida, United States, 33980

Actively Recruiting

15

Neurocrine Clinical Site

Tampa, Florida, United States, 33629

Actively Recruiting

16

Neurocrine Clinical Site

Augusta, Georgia, United States, 30912

Actively Recruiting

17

Neurocrine Clinical Site

Marietta, Georgia, United States, 30060

Actively Recruiting

18

Neurocrine Clinical Site

Naperville, Illinois, United States, 60563

Actively Recruiting

19

Neurocrine Clinical Site

Omaha, Nebraska, United States, 68124

Actively Recruiting

20

Neurocrine Clinical Site

Independence, Ohio, United States, 44131

Actively Recruiting

21

Neurocrine Clinical Site

Richmond, Virginia, United States, 23226

Actively Recruiting

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Research Team

N

Neurocrine Medical Information Call Center

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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