Actively Recruiting

Phase 2
Age: 50Years +
All Genders
NCT07275840

A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD

Led by Innovent Biologics Technology Limited (Shanghai R&D Center) · Updated on 2026-01-08

800

Participants Needed

1

Research Sites

38 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is designed for Open-label, multi-center, single-arm Phase II trail to evaluate the efficacy and safety of intravitreal injection of IBI302 in nAMD patients.

CONDITIONS

Official Title

A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent form before participating
  • Male or female aged 50 years or older at consent
  • Active choroidal neovascularization (CNV) under or involving the macular fovea due to nAMD
  • Best corrected visual acuity of the study eye between 19 and 78 ETDRS letters at baseline
Not Eligible

You will not qualify if you...

  • Ocular or systemic diseases in the study eye that may interfere with treatment response or study results
  • Uncontrollable glaucoma in the study eye
  • Active intraocular or periocular infection or inflammation in either eye
  • Severe visual function disorders in the non-study eye
  • Anti-VEGF treatment in the study eye within 90 days before baseline
  • Anti-complement treatment in the study eye within 90 days before baseline
  • Prior IBI302 treatment in the study eye before baseline
  • Uncontrollable hypertension
  • Glycated hemoglobin (HbA1c) above 10.0% within 28 days before screening
  • Other exclusion criteria per protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai general hospital

Shanghai, Shanghai Municipality, China, P. R. China 200080

Actively Recruiting

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Research Team

Y

Yating Liu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD | DecenTrialz