Actively Recruiting
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Led by Inmagene LLC · Updated on 2026-02-19
220
Participants Needed
23
Research Sites
119 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the efficacy and safety of different dose regimens of IMG-007, compared to placebo.
CONDITIONS
Official Title
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 74 years
- Moderate-to-severe atopic dermatitis
- History of inadequate response or intolerance to stable topical treatment before screening, or topical treatments are inadvisable
- Female participants not pregnant or breastfeeding and either not of childbearing potential or agree to use a highly effective contraception method
- Male participants agree to use a highly effective contraception method
- Eczema Area and Severity Index (EASI) score of 16 or higher
- Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) score of 3 or higher
- At least 10% body surface area affected by atopic dermatitis
- Mean peak itch score of 4 or more during 7 days before randomization
You will not qualify if you...
- Positive test for hepatitis B, hepatitis C, or HIV infection
- Evidence of active or latent tuberculosis
- History of untreated or inadequately treated tuberculosis
- Active infection requiring systemic treatment with antibiotics, antivirals, antifungals, antiparasitics, or antiprotozoals
- Unstable itchy skin conditions other than atopic dermatitis that interfere with assessment
- Other medical conditions or lab abnormalities increasing risk or interfering with study participation or results
- Receipt of specified therapies within defined timeframes before baseline visit
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 23 locations
1
Antelope Valley Clinical Trials
Lancaster, California, United States, 93534
Actively Recruiting
2
UCLA Division of Dermatology
Los Angeles, California, United States, 90095
Actively Recruiting
3
Renstar Medical Research
Ocala, Florida, United States, 34470
Actively Recruiting
4
Palm Harbor Dermatology PA d/b/a TrueBlue Clinical Research
Tampa, Florida, United States, 33609
Actively Recruiting
5
Arlington Dermatology
Rolling Meadows, Illinois, United States, 60008
Actively Recruiting
6
Forest Hills Dermatology Group
Kew Gardens, New York, United States, 11415
Actively Recruiting
7
Inmagene Site 1
New York, New York, United States, 10029
Actively Recruiting
8
Vitality Clinical Trials LLC
Woodbury, New York, United States, 11797
Actively Recruiting
9
Darst Dermatology
Charlotte, North Carolina, United States, 28277
Actively Recruiting
10
Red River Research Partners, LLC
Fargo, North Dakota, United States, 58103
Actively Recruiting
11
ClinOhio Research Services LLC.
Columbus, Ohio, United States, 43213
Actively Recruiting
12
Apex Clinical Research Center
Mayfield Heights, Ohio, United States, 44124
Actively Recruiting
13
Oregon Dermatology and Research Center
Portland, Oregon, United States, 97210
Actively Recruiting
14
Palmetto Clinical Trial Services, LLC
Anderson, South Carolina, United States, 29621
Actively Recruiting
15
Stryde Research-Epiphany Dermatology
Southlake, Texas, United States, 76092
Actively Recruiting
16
Dermatology of Seattle & Bellevue
Burien, Washington, United States, 698168
Actively Recruiting
17
Dr. Chin-ho-Hong Medical Inc.
Surrey, British Columbia, Canada, V3R 6A7
Actively Recruiting
18
PacificDerm
Vancouver, British Columbia, Canada, V6H 4B1
Actively Recruiting
19
Sudbury Skin Clinique
Greater Sudbury, Ontario, Canada, P3C 1X8
Actively Recruiting
20
DermEdge Research
Mississauga, Ontario, Canada, L4Y 4C5
Actively Recruiting
21
North Bay Dermatology Centre
North Bay, Ontario, Canada, P1B 3Z7
Actively Recruiting
22
Innovaderm Research Inc.
Montreal, Quebec, Canada, H2X 2V1
Actively Recruiting
23
Skinsense Medical Research
Saskatoon, Saskatchewan, Canada, S7K 2C1
Actively Recruiting
Research Team
A
ADAPTIVE Study Lead
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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