Evaluating a Nutritional Supplement with Bergamot and Artichoke to Lower Cholesterol in Adults with Mild to Moderate Hypercholesterolemia

What this Trial Is About

This research aims to evaluate the effectiveness of a nutritional supplement containing bergamot, artichoke, and other ingredients in reducing cholesterol levels, specifically low-density lipoprotein LDL, in patients with moderate or mild hypercholesterolemia. The study compares this supplement to maintaining healthy lifestyle habits and examines additional effects on lipid profiles, anthropometric data, vital signs, treatment adherence, safety, and satisfaction over four months. Participants are randomly assigned to one of three groups one taking one capsule of the supplement nightly, another taking two capsules nightly, and a control group that does not take the supplement but receives guidance on a healthy lifestyle and active living. The treatment period lasts four months, during which the supplement is taken at dinner with water. All participants receive lifestyle advice consistent with usual clinical practice. Throughout the study, participants undergo evaluations including measurements of weight, body mass index, waist circumference, blood pressure, pulse, and blood tests assessing cholesterol types, triglycerides, liver and kidney function, and Liposcale analysis. These assessments occur at baseline, and after two and four months. Researchers monitor changes in LDL cholesterol and other lipid parameters to assess the supplements impact while also tracking safety and adherence. Total participation spans the four-month treatment period.

Study To Evaluate The Efficacy And Safety Of A Nutritional Supplement Based On Bergamot, Artichoke And Other Ingredients For Reducing Cholesterol Levels In Patients With Hypercholesterolemia (Metachol+)