Actively Recruiting

Phase 3
Age: 18Years - 75Years
All Genders
NCT06754644

A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC

Led by Qilu Pharmaceutical Co., Ltd. · Updated on 2025-06-10

808

Participants Needed

1

Research Sites

97 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the efficacy similarities between QL2107 and Keytruda in metastatic non-squamous NSCLC.

CONDITIONS

Official Title

A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years
  • Voluntarily agree to participate and able to follow study procedures
  • Confirmed metastatic (stage IV) non-squamous NSCLC according to AJCC 8th Edition
  • No EGFR sensitive mutations or ALK gene translocations
  • Expected survival of at least 3 months
  • ECOG performance status score of 0 or 1
Not Eligible

You will not qualify if you...

  • Pulmonary radiation therapy greater than 30 Gy within 6 months before first dose
  • Palliative radiation therapy completed within 7 days before first dose
  • Need for any other anti-tumor therapy during the study
  • Uncontrolled or symptomatic pericardial effusion, pleural effusion, or ascites requiring repeated drainage
  • Brain stem, meninges, or spinal cord metastases or compression

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shandong First Medical University Cancer Hospital

Jinan, Shandong, China

Actively Recruiting

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Research Team

J

Jinming Yu, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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