Actively Recruiting

Phase 2
Age: 18Years - 50Years
All Genders
NCT06311890

Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne

Led by Xiyuan Hospital of China Academy of Chinese Medical Sciences · Updated on 2024-03-15

46

Participants Needed

1

Research Sites

138 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the clinical efficacy, safety and tolerability of a photodynamic therapy(PDT) based on a new photosensitizer, Chlorin-e6, in the treatment of moderate to severe acne. The hypothesis is that the therapy has good efficacy, safety and tolerability.

CONDITIONS

Official Title

Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne

Who Can Participate

Age: 18Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or non-pregnant female between 18 and 50 years old
  • Diagnosed with moderate to severe facial acne vulgaris
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Taking photosensitive drugs
  • Allergic to any component of the photosensitizer
  • Allergies to porphyrins or history of photosensitivity
  • Pregnant, lactating, or planning pregnancy within 3 months
  • Used oral or topical antibiotics, retinoids, glucocorticoids, peroxybenzoyl, or similar drugs within 1 month
  • Sunlight exposure in past month, photoelectric treatment in past 3 months, or facial grinding treatment in past 6 months
  • Using vasodilators, beta blockers, anticoagulants, or drugs causing facial capillary dilation
  • Having facial rosacea, atopic dermatitis, hormone-dependent dermatitis, or other facial skin diseases
  • Abnormal blood/urine tests, liver/kidney function issues, important organ diseases, or hematopoietic system disorders
  • Participating in other clinical trials simultaneously

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xiyuan Hospital of China Academy of Chinese Medical Sciences Organization

Beijing, China, 100091

Actively Recruiting

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Research Team

H

Huiyan Chi, doctor

CONTACT

Y

Yisheng Zhang, doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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