Actively Recruiting

Phase 3
Age: 2Years - 17Years
All Genders
NCT03893045

A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects

Led by AMAG Pharmaceuticals, Inc. · Updated on 2026-04-17

75

Participants Needed

15

Research Sites

367 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a Phase 3, randomized, open-label, multicenter, study in male and female pediatric subjects (2 years to \<18 years of age) with IDA, or felt by their clinician to be at risk of developing IDA. This study allows for enrollment of subjects with IDA regardless of etiology, except for CKD subjects (pediatric CKD subjects are being studied in a separate ferumoxytol protocol).

CONDITIONS

Official Title

A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects

Who Can Participate

Age: 2Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 2 years to under 18 years at consent
  • Diagnosis of iron deficiency anemia with hemoglobin below 11.0 g/dL and at least one of: transferrin saturation below 20% or ferritin below 100 ng/mL
  • History of unsatisfactory oral iron therapy, intolerance to oral iron, or medical inappropriateness for oral iron
Not Eligible

You will not qualify if you...

  • Known allergy to ferumoxytol or iron sucrose components
  • History of allergy to intravenous iron
  • History of two or more significant drug allergies
  • Chronic kidney disease with eGFR below 60 mL/min/1.73 m2 or requiring dialysis
  • Low systolic blood pressure below age-specific thresholds
  • Hemoglobin 7.0 g/dL or lower
  • Serum ferritin level above 600 ng/mL

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 15 locations

1

Arkansas Children's Hospital

Little Rock, Arkansas, United States, 72202

Not Yet Recruiting

2

University of Florida

Gainesville, Florida, United States, 32608

Not Yet Recruiting

3

Optimus U Corporation

Miami, Florida, United States, 33125

Actively Recruiting

4

Biomedical Research LLC

Miami, Florida, United States, 33184

Actively Recruiting

5

Gwinnett Research Institute

Buford, Georgia, United States, 30519

Not Yet Recruiting

6

Sun Research Institute

San Antonio, Texas, United States, 78215

Actively Recruiting

7

JSC Saules seimos medicinos centras

Kaunas, Lithuania

Not Yet Recruiting

8

Klaipeda Children's Hospital

Klaipėda, Lithuania

Not Yet Recruiting

9

Children's Hospital-Affiliate of Vilnius University Hospital Santariskiu Klinikos

Vilnius, Lithuania

Not Yet Recruiting

10

Osrodek Badan Klinicznych In Vivo sp. z o.o.

Bydgoszcz, Poland

Not Yet Recruiting

11

Prywatny Gabinet Lekarski Dr N. med. Jerzy Brzostek

Dębica, Poland

Not Yet Recruiting

12

Pro Familia Altera Sp. z o.o.

Katowice, Poland

Not Yet Recruiting

13

Korczowski Bartosz, Gabinet Lekarski

Rzeszów, Poland

Not Yet Recruiting

14

Centrum Zdrowia MDM

Warsaw, Poland

Not Yet Recruiting

15

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu

Wroclaw, Poland

Not Yet Recruiting

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Research Team

C

Clinical Trial Interest

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects | DecenTrialz