Actively Recruiting

Phase 4
Age: 19Years +
All Genders
NCT05427786

A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT ReductioN of DecREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease

Led by Korea University Anam Hospital · Updated on 2024-10-10

460

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study was to determine the effect of intra-coronary administration of nicorandil on the prevention of lowering of coronary blood flow for high-risk plaque lesions defined as the high value of lipid core burden index in patients with coronary artery disease who require stent treatment.

CONDITIONS

Official Title

A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT ReductioN of DecREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 19 years old
  • Agree to the study plan and clinical follow-up, and provide written consent
  • Undergoing NIRS-IVUS guided coronary stent surgery for coronary artery disease
Not Eligible

You will not qualify if you...

  • TIMI flow less than or equal to 2 before coronary intervention
  • Known allergy or contraindication to heparin, aspirin, clopidogrel, ticagrelor, prasugrel, rosuvastatin, ezetimibe, evolocumab, lansoprazole, cobalt chromium, stainless steel nickel, or contrast agents (except controlled contrast allergy without anaphylaxis)
  • Pregnant, breastfeeding, or planning pregnancy during the study
  • Planning surgery to stop antiplatelet drugs within 6 months of registration
  • Life expectancy less than 1 year
  • Hospitalized for cardiogenic shock with low survival prognosis by medical judgment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Korea University Anam Hospital

Seoul, South Korea

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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