Actively Recruiting
A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer
Led by Theravectys S.A. · Updated on 2026-02-02
72
Participants Needed
4
Research Sites
120 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn about the safety and efficacy of a potential new treatment called Lenti-HPV-07 in patients with a cancer induced by Human Papilloma Virus (HPV). The main questions aim to answer are: * Is Lenti-HPV-07 safe? * Does Lenti-HPV-07 induce an immune response? Participants will be assigned to a group based on their cancer type * either study drug group A: recurrent and/or metastatic cancer * or study drug group B: newly diagnosed with locally advanced cancer After they finish the study treatment, they will be followed for up to 1 year. Follow-up visits will occur via clinic visits or phone calls 4 weeks after the last study treatment and then quarterly for up to 1 year.
CONDITIONS
Official Title
A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed invasive HPV-related oropharyngeal or cervical cancer
- ECOG performance status of 0 or 1
- Adequate hepatic, renal, pulmonary, and bone marrow/hematological function
You will not qualify if you...
- Seropositivity for HIV
- Active hepatitis C virus (HCV) infection
- Active hepatitis B (HBV) infection
AI-Screening
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Trial Site Locations
Total: 4 locations
1
Florida Cancer Specialists (from Sarah Canon research Institute)
Orlando, Florida, United States, 32827
Actively Recruiting
2
Tampa General Hospital
Tampa, Florida, United States, 33606
Actively Recruiting
3
Moffitt Cancer Center
Tampa, Florida, United States, 33612
Actively Recruiting
4
Oklahoma Cancer Specialists and Research Institute, LLC
Tulsa, Oklahoma, United States, 74146
Actively Recruiting
Research Team
D
Daniel Loera
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
2
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