Actively Recruiting

Age: 18Years +
All Genders
NCT07052396

Study to Evaluate Long-term Effectiveness and Safety, Patient Characteristics and Subjective Patient-reported Outcomes of Dupilumab in Patients With Chronic Obstructive Pulmonary Disease (COPD) Under Real-world Conditions

Led by Sanofi · Updated on 2025-12-22

350

Participants Needed

18

Research Sites

208 weeks

Total Duration

On this page

Sponsors

S

Sanofi

Lead Sponsor

R

Regeneron Pharmaceuticals

Collaborating Sponsor

AI-Summary

What this Trial Is About

Study to evaluate the change of health-related quality of life, patient characteristics, efficacy and safety in Chronic Obstructive Pulmonary Disease (COPD) patients with Dupilumab therapy in a real-world setting over 24 months.

CONDITIONS

Official Title

Study to Evaluate Long-term Effectiveness and Safety, Patient Characteristics and Subjective Patient-reported Outcomes of Dupilumab in Patients With Chronic Obstructive Pulmonary Disease (COPD) Under Real-world Conditions

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing and able to sign informed consent for use of pseudonymized clinical data
  • Adults aged 18 years or older
  • Diagnosed with uncontrolled COPD despite treatment with LAMA/LABA/ICS (or LAMA/LABA if ICS not appropriate) and have elevated blood eosinophils
  • Newly started on Dupilumab treatment as indicated in the approved product guidelines, independent of study participation
Not Eligible

You will not qualify if you...

  • Not eligible for Dupilumab treatment according to approved guidelines
  • Participation in any interventional or observational study currently or within 12 months before enrollment that may affect study assessments
  • Any acute or chronic condition that may limit ability to complete questionnaires or participate or affect study results as judged by the doctor
  • Hospitalized due to COPD exacerbation within 4 weeks prior to enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 18 locations

1

Investigational Site Number: DE18

Auerbach, Germany, 08209

Actively Recruiting

2

Investigational Site Number: DE21

Augsburg, Germany, 86152

Actively Recruiting

3

Investigational Site Number: DE13

Bad Homburg, Germany, 61350

Actively Recruiting

4

Investigational Site Number: DE19

Berlin, Germany, 10717

Actively Recruiting

5

Investigational Site Number: DE02

Berlin, Germany, 14163

Actively Recruiting

6

Investigational Site Number: DE29

Burgwedel, Germany, 30938

Actively Recruiting

7

Investigational Site Number: DE01

Darmstadt, Germany, 64283

Actively Recruiting

8

Investigational Site Number: DE09

Erkelenz, Germany, 41812

Actively Recruiting

9

Investigational Site Number: DE06

Flensburg, Germany, 24937

Actively Recruiting

10

Investigational Site Number: DE08

Fürstenwalde, Germany, 15517

Actively Recruiting

11

Investigational Site Number: DE03

Hamburg, Germany, 20354

Actively Recruiting

12

Investigational Site Number: DE04

Hamburg, Germany, 22459

Actively Recruiting

13

Investigational Site Number: DE07

Hohenstein-Ernstthal, Germany, 09337

Actively Recruiting

14

Investigational Site Number: DE10

Itzehoe, Germany, 25524

Actively Recruiting

15

Investigational Site Number: DE24

Kaiserslauten, Germany, 67655

Actively Recruiting

16

Investigational Site Number: DE25

Lüneburg, Germany, 21339

Actively Recruiting

17

Investigational Site Number: DE20

Marburg, Germany, 35037

Actively Recruiting

18

Investigational Site Number: DE14

Markkleeberg, Germany, 04416

Actively Recruiting

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Research Team

T

Trial Transparency email recommended (Toll free for US & Canada)

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Study to Evaluate Long-term Effectiveness and Safety, Patient Characteristics and Subjective Patient-reported Outcomes of Dupilumab in Patients With Chronic Obstructive Pulmonary Disease (COPD) Under Real-world Conditions | DecenTrialz