Actively Recruiting
A Study to Evaluate Microvessel Ultrasound Imaging of Wound Healing in Patients With Chronic Ulcers
Led by Mayo Clinic · Updated on 2026-01-22
10
Participants Needed
1
Research Sites
157 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research is to explore the use of high-resolution microvessel ultrasound imaging system to look for scarring and to monitor wound healing and to see if treatment affects the amount of tiny vessels and circulation around the wound.
CONDITIONS
Official Title
A Study to Evaluate Microvessel Ultrasound Imaging of Wound Healing in Patients With Chronic Ulcers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chronic wound lasting at least 6 weeks from diabetic foot ulcers and/or lower extremity venous ulcers with wound surface between 2 and 15 sq. cm and no active infection at enrollment
- Wound shows less than 50% size reduction after 30 days of standard care treatment
- For venous ulcers, ultrasound shows venous reflux greater than 0.5 seconds
- Good blood sugar control: fasting glucose not more than 110 mg% and HbA1c less than 6.5%
- Adequate blood supply to the wound confirmed by foot tissue oxygen level (TCPO2 > 30 mmHg) in neuropathic diabetic foot syndrome patients
- For wounds with ischemic component, clinical improvement in limb blood supply after revascularization procedure documented by ultrasound
- Ankle-brachial index (ABI) equal to or above 0.8
You will not qualify if you...
- Acute wound duration less than 6 weeks
- Active wound infection or current antibiotic use
- Smoking
- For venous ulcers, ultrasound shows venous reflux less than 0.5 seconds
- Poor blood sugar control: fasting glucose more than 110 mg% or HbA1c not less than 6.5%
- Poor blood supply to wound confirmed by foot tissue oxygen level (TCPO2 less than 30 mmHg) in neuropathic diabetic foot syndrome patients
- Ankle-brachial index (ABI) less than 0
- Pregnancy
- Known allergy to lidocaine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic Minnesota
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
M
Michael R Moynagh, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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