Actively Recruiting
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Led by Poitiers University Hospital · Updated on 2025-12-29
15
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease. This pilot study aims to show the interest of alternative non-pharmacological measures such as a digital music therapy tool, adapted to an audience of Huntington's patients, to help manage the psychobehavioral symptoms frequently observed in this affection, and to avoid breakdowns due to caregiver exhaustion.
CONDITIONS
Official Title
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age �38; 18 years
- Genetically confirmed Huntington disease with at least 35 CAG repeats in the HTT gene
- Unified Huntington's disease Rating Scale (UHDRS) score �38; 5 with diagnostic confidence score of 4
- No significant cognitive impairment with a MoCA score �3E= 24
- Stable drug treatment for at least 28 days before and during the study
- No legal guardianship or subordination
- Affiliated with a health insurance system as required by French biomedical research law
- Provided written informed consent to participate
You will not qualify if you...
- Unable to give free and informed consent
- Significant hearing impairment
- Currently participating in another study at time of enrollment
- Persons under enhanced protection such as judicial or administrative liberty deprivation, adults under legal guardianship, or patients in vital emergency situations
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
CHU Poitiers / CIC
Poitiers, France, 86000
Actively Recruiting
Research Team
I
Isabelle BENATRU, Dr
CONTACT
C
Claire LAFAY-CHEBASSIER, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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