A Double-Blind Study to Test a Postbiotic Supplement for Supporting Weight Loss and Metabolic Health in Adults Aged 18 to 65

What this Trial Is About

Researchers are evaluating the effects of a specific oral postbiotic supplement on metabolic health in overweight adults. The study focuses on how this supplement may influence weight loss, body mass index BMI, appetite control, blood metabolic markers, and related factors over an eight-week period. The trial addresses obesity-related metabolic dysfunction linked to gut microbiome changes, aiming to explore microbiome-based interventions for better weight and metabolic health management. Participants will be randomly assigned to one of two groups in a double-blind design one group receives a daily capsule containing 40 mg of the postbiotic along with an herbal and vitamin blend, while the other group receives a daily placebo capsule. The intervention lasts for eight weeks, with the postbiotic group receiving active ingredients such as Vitamin D, Vitamin B12, Chromium, and a specific Lactobacillus plantarum strain, combined with herbal extracts. The placebo contains inactive ingredients only. During the study, participants will be monitored through various assessments including measurements of weight, BMI, food cravings, and blood tests for metabolic markers. Additional evaluations include depression scores and gut microbiome analysis. Safety is continuously assessed by tracking adverse events. Participants are expected to maintain their usual diet and physical activity, avoid other probiotic or postbiotic supplements, and comply with study procedures throughout the eight weeks.

A Study to Evaluate a Postbiotic in Supporting Weight Loss and Metabolic Health