Actively Recruiting

Phase 2
Age: 21Years +
All Genders
Healthy Volunteers
NCT06428448

Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections

Led by OsteoRemedies, LLC · Updated on 2026-04-17

60

Participants Needed

3

Research Sites

95 weeks

Total Duration

On this page

Sponsors

O

OsteoRemedies, LLC

Lead Sponsor

M

MCRA

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is being conducted to evaluate the safety and effectiveness of the REMEDY SPECTRUM IM Spacer Nail in the treatment of ankle-related infections. The study is expected to take approximately 18 months from first subject enrolled to the last follow-up visit. It will have a 12-month enrollment period and a 6-month follow-up. This study is a Prospective, multicenter, single-arm clinical trial. All subjects enrolled in this study will receive the REMEDY SPECTRUM IM Spacer Nail.

CONDITIONS

Official Title

Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 21 years of age or older
  • Have an ankle-related infection
  • Be skeletally mature with closed epiphyses
  • Be able to give voluntary, written informed consent
  • Be willing and able to follow all study procedures before and after surgery
  • If female and able to have children, have a negative pregnancy test before surgery and no plans to become pregnant until study completion
Not Eligible

You will not qualify if you...

  • Infection not involving the ankle
  • Known immunodeficiency or recent immunosuppressive or radiation therapy within 6 months before surgery
  • Dysvascular affected limb
  • Inability to achieve adequate soft-tissue coverage
  • Mental or psychological disorders impairing questionnaire completion
  • Currently pregnant, breastfeeding, or planning pregnancy/breastfeeding during the study
  • Currently a prisoner
  • Medical or other conditions that could prevent follow-up visits or proper post-operative activity
  • Allergy to vancomycin or gentamicin
  • Implanted with other antibiotic eluting products

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

University of Michigan Health - Sparrow Clinical Research Institute

Lansing, Michigan, United States, 48190

Actively Recruiting

2

OrthoCarolina Research Institute

Charlotte, North Carolina, United States, 28207

Actively Recruiting

3

Duke University Medical Center

Durham, North Carolina, United States, 27710

Actively Recruiting

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Research Team

C

Crystal Djaba

CONTACT

J

Jacob Schafer

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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