Actively Recruiting
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age)
Led by ModernaTX, Inc. · Updated on 2026-05-11
350
Participants Needed
8
Research Sites
132 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical study will evaluate the safety, reactogenicity, and immunogenicity of monovalent mRNA-1982, a messenger ribonucleic acid (mRNA) vaccine to prevent Lyme disease in healthy adults aged 18 to 70 years old.
CONDITIONS
Official Title
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 70 years old
- Be in good general health as determined by medical evaluation including medical history and physical exam
- Use contraception consistent with local regulations for clinical study participation
You will not qualify if you...
- History of severe allergic reaction requiring medical intervention to any mRNA vaccine or its components
- Have a chronic illness related to Lyme disease or active symptomatic Lyme disease infection
- Received treatment for Lyme disease within the prior 3 months
- Previously vaccinated against Lyme disease or participated in any Lyme disease vaccine study
- Had a tick bite within 4 weeks prior to Day 1
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
Colchester Research Group
Truro, Nova Scotia, Canada, B2N 1L2
Actively Recruiting
2
Bluewater Clinical Research Group Inc.
Sarnia, Ontario, Canada, N7T 4X3
Not Yet Recruiting
3
Stouffville Medical Research Institute Inc.
Stouffville, Ontario, Canada, L4A 1H2
Not Yet Recruiting
4
Dr. Anil K. Gupta Medicine Professional Corporation Inc.
Toronto, Ontario, Canada, M9V 4B4
Not Yet Recruiting
5
Diex Recherche Inc. - Division Joliette
Joliette, Quebec, Canada, J6E 6A9
Not Yet Recruiting
6
Diex Recherche Inc. - Division Sherbrooke
Sherbrooke, Quebec, Canada, J1L 0H8
Not Yet Recruiting
7
Diex Recherche Inc. - Division Victoriaville
Victoriaville, Quebec, Canada, G6P 3Z8
Not Yet Recruiting
8
Diex Recherche Inc. - Division Quebec
Québec, Canada, G1V 4T3
Not Yet Recruiting
Research Team
M
Moderna WeCare Team
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here