Actively Recruiting

Phase 1
Age: 12Years - 30Years
All Genders
Healthy Volunteers
NCT06655324

A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).

Led by Merck Sharp & Dohme LLC · Updated on 2026-04-13

250

Participants Needed

9

Research Sites

188 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Epstein Barr virus (EBV) is a virus which can cause infectious mononucleosis and is associated with certain kinds of cancer and multiple sclerosis. Researchers are looking for new ways to prevent disease related to EBV and have developed a new study vaccine (V350A and V350B). The main goal of this study is to learn about the safety and tolerability of V350A and V350B in healthy adults.

CONDITIONS

Official Title

A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).

Who Can Participate

Age: 12Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be in good health before randomization
  • Have a body mass index between 18 and 38 kg/m² for ages 18 to 30
  • Have a body mass index between 15 and 38 kg/m² for ages 12 to 17
Not Eligible

You will not qualify if you...

  • Have had infectious mononucleosis within 12 months before enrollment
  • Have any immunosuppressive medical condition or be receiving immunosuppressive therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

California Clinical Trials Medical Group managed by PAREXEL ( Site 0011)

Glendale, California, United States, 91206

Completed

2

QPS-MRA, LLC ( Site 0012)

Miami, Florida, United States, 33143

Active, Not Recruiting

3

Alliance for Multispecialty Research, LLC ( Site 0008)

Kansas City, Missouri, United States, 64114

Actively Recruiting

4

Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0016)

Springfield, Missouri, United States, 65802

Actively Recruiting

5

Velocity Clinical Research Lincoln ( Site 0004)

Lincoln, Nebraska, United States, 68510

Actively Recruiting

6

Velocity Clinical Research, Omaha ( Site 0005)

Omaha, Nebraska, United States, 68134

Active, Not Recruiting

7

Remington-Davis, Inc. ( Site 0017)

Columbus, Ohio, United States, 43215

Actively Recruiting

8

Lynn Health Science Institute ( Site 0010)

Oklahoma City, Oklahoma, United States, 73112

Actively Recruiting

9

Alliance for Multispecialty Research, LLC ( Site 0009)

Knoxville, Tennessee, United States, 37909

Active, Not Recruiting

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Research Team

T

Toll Free Number

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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