Actively Recruiting

Phase 1
Age: 18Years - 75Years
All Genders
NCT06390774

A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SSGJ-705 Monotherapy in Patients with Advanced Malignant Tumors

Led by Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. · Updated on 2024-10-18

180

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study was an open-label phase I study to evaluate the safety, tolerability, PK profile and potential efficacy of SSGJ-705 as a single agent in patients with advanced malignancies.

CONDITIONS

Official Title

A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SSGJ-705 Monotherapy in Patients with Advanced Malignant Tumors

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females aged over 18 years
  • Histologically or cytologically confirmed locally advanced, recurrent, or metastatic malignancies
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Expected survival time greater than 3 months
  • Signed informed consent form
  • Adequate organ function
Not Eligible

You will not qualify if you...

  • Any adverse events greater than grade 1 from prior anti-tumor treatments, except hair loss, fatigue, and grade 2 peripheral neurotoxicity
  • Pregnant or nursing women or men and women planning to have children
  • Symptomatic metastasis in the central nervous system
  • Allergic reactions to antibody drugs or any components of the study drug
  • Severe difficulty breathing at rest due to cancer complications or need for supplemental oxygen
  • Participation in another clinical study involving medical devices or drugs within one month prior to screening, except non-intervention or follow-up studies

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Affiliated Cancer Hospital of Shandong First Medical University

Jinan, Shandong, China

Actively Recruiting

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Research Team

J

Jinming Yu, MD,Ph.D

CONTACT

Y

Yuping Sun, MD,Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

4

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