Actively Recruiting
A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use
Led by Vanda Pharmaceuticals · Updated on 2026-04-20
280
Participants Needed
10
Research Sites
35 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to measure the effects of using Tradipitant to treat nausea and vomiting induced by GLP-1R agonist use in adults with class I or class II obesity, or adults who are overweight with at least one weight-related condition. The study is placebo-controlled with two treatment arms.
CONDITIONS
Official Title
A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Body Mass Index 65 25 and < 40 kg/m�b2
- No serious medical problems or chronic diseases, specifically no type I or type II diabetes
You will not qualify if you...
- Another disorder that contributes to gastrointestinal symptoms
- History of intolerance and/or hypersensitivity to NK-1 receptor antagonists
- History of intolerance and/or hypersensitivity to GLP-1 receptor agonists
- Exposure to any investigational medication within the past 60 days
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
Vanda Investigational Site
Los Angeles, California, United States, 90025
Actively Recruiting
2
Vanda Investigational Site
San Diego, California, United States, 92108
Actively Recruiting
3
Vanda Investigational Site
San Jose, California, United States, 95124
Not Yet Recruiting
4
Vanda Investigational Site
Tampa, Florida, United States, 33613
Actively Recruiting
5
Vanda Investigational Site
Hamilton, New Jersey, United States, 08690
Not Yet Recruiting
6
Vanda Investigational Site
New York, New York, United States, 10016
Not Yet Recruiting
7
Vanda Investigational Site
Syosset, New York, United States, 11791
Not Yet Recruiting
8
Vanda Investigational Site
Plano, Texas, United States, 75024
Not Yet Recruiting
9
Vanda Investigational Site
San Antonio, Texas, United States, 78215
Not Yet Recruiting
10
Vanda Investigational Site
Burke, Virginia, United States, 22015
Not Yet Recruiting
Research Team
V
Vanda Pharmaceuticals
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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