Actively Recruiting
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
Led by Merck Sharp & Dohme LLC · Updated on 2026-05-04
140
Participants Needed
6
Research Sites
194 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are looking for new ways to treat Psoriatic Arthritis (PsA). This study will help find out if a study medicine called tulisokibart (MK-7240) can treat symptoms of active PsA. This study assesses the efficacy, safety, and tolerability of tulisokibart in adult participants with active PsA. In this study, researchers will look at different doses of tulisokibart. Researchers want to learn if at least one of the study doses of tulisokibart works better than a placebo to lessen PsA symptoms. A placebo looks like the study medicine but has no study medicine in it. Using a placebo helps researchers better understand the effects of the study medicine.
CONDITIONS
Official Title
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 80 years
- Clinical diagnosis of Psoriatic Arthritis fulfilling CASPAR criteria with symptoms starting at least 6 months before screening
- Diagnosis or history of active plaque psoriasis
- History of no prior biologic DMARD treatment or inadequate response/intolerance to biologic DMARDs
You will not qualify if you...
- Arthritis symptoms starting before age 17 or diagnosis of other inflammatory joint diseases besides Psoriatic Arthritis
- Skin conditions other than psoriasis that affect psoriasis assessment
- History of cancer except fully treated nonmelanoma skin cancers or cervical carcinoma in situ, disease-free for less than 5 years before randomization
- Any active infection
- Known allergies or intolerance to tulisokibart or its ingredients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Arizona Arthritis & Rheumatology Associates, P.C. - Tucson ( Site 5120)
Tucson, Arizona, United States, 85704-1140
Actively Recruiting
2
Arthritis and Rheumatism Associates - Rockville ( Site 5127)
Rockville, Maryland, United States, 20850
Actively Recruiting
3
Altoona Center for Clinical Research ( Site 5110)
Duncansville, Pennsylvania, United States, 16635
Actively Recruiting
4
Articularis Healthcare Group dba: Low Country Rheumatology ( Site 5128)
Summerville, South Carolina, United States, 29486
Actively Recruiting
5
Greater Houston Rheumatology ( Site 5103)
Houston, Texas, United States, 77095
Actively Recruiting
6
Centre de Recherche Musculo-Squelettique ( Site 5202)
Trois-Rivières, Quebec, Canada, G9A 3Y2
Actively Recruiting
Research Team
T
Toll Free Number
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here