Actively Recruiting

Phase Not Applicable
Age: 13Years +
All Genders
NCT06387485

A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning

Led by Ricoh USA, Inc. · Updated on 2026-02-06

150

Participants Needed

3

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This prospective, multi-center, randomized controlled study aims to assess the efficacy of utilizing 3D printed models in preoperative planning for the excision of tumors involving bony structures within the body. The study is expected to last approximately 12 months and involve up to 150 subjects across up to 5 sites. Subjects will be randomized in a 1:1 ratio into either the experimental arm, utilizing 3D printed models and imaging, or the active comparator arm, using only imaging. Primary endpoint: Operative time of surgical procedure. Secondary endpoints: Reduction of blood loss, proportion of postoperative adverse events, and negative tumor margins. Exploratory endpoints: Surgical planning ease, changes in surgical plan, and surgeon satisfaction.

CONDITIONS

Official Title

A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning

Who Can Participate

Age: 13Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects must be at least 13 years of age
  • Subjects must be able to provide written informed consent
  • Subjects must have tumor(s) invading bone requiring surgical excision, including craniomaxillofacial, spine, long bone, or pelvis tumors
  • Subjects must agree to have quality cross-sectional imaging for 3D model development
Not Eligible

You will not qualify if you...

  • Pregnant or nursing women
  • Subjects with serious systemic diseases
  • Subjects with clotting disorders
  • Subjects with uncontrolled high blood pressure
  • Subjects who are HIV-positive
  • Subjects unable to be randomized due to surgical team preference
  • Subjects whose anatomy has changed substantially since imaging was obtained
  • Subjects considered poor candidates for surgery or study due to medical, social, or psychological reasons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Kaiser Permanente Oakland Medical Center

Oakland, California, United States, 94611

Actively Recruiting

2

William Beaumont University Hospital

Royal Oak, Michigan, United States, 48073

Actively Recruiting

3

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States, 43212

Actively Recruiting

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Research Team

A

Alexandra Gormley, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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