Actively Recruiting
Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
Led by InSilico Medicine Hong Kong Limited · Updated on 2025-11-12
40
Participants Needed
12
Research Sites
107 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this revised Phase IIa study is to demonstrate safety of INS018\_055 over 12 weeks in adults with Idiopathic Pulmonary Fibrosis (IPF).
CONDITIONS
Official Title
Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patients aged 640 years based on the date of the written informed consent form
- Diagnosis of idiopathic pulmonary fibrosis (IPF) as defined by recognized respiratory society guidelines
- Stable health condition suitable for study participation based on medical history, physical examination, vital signs, ECG, and laboratory evaluation
- During screening, forced vital capacity (FVC) 640% predicted normal
- During screening, diffusing capacity of the lungs for carbon monoxide (DLCO) corrected for hemoglobin 625% and <80% predicted normal
- During screening, forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) ratio >0.7 based on pre-bronchodilator value
You will not qualify if you...
- Acute IPF exacerbation within 4 months prior to study start
- Unwillingness to refrain from smoking within 3 months prior to screening and throughout the study
- Female patients who are pregnant or nursing
- Abnormal ECG findings
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 12 locations
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
Actively Recruiting
2
HonorHealth Research Institute
Scottsdale, Arizona, United States, 85258
Actively Recruiting
3
Keck School of Medicine of USC
Los Angeles, California, United States, 90033
Actively Recruiting
4
Florida Lung Asthma and Sleep Specialist
Celebration, Florida, United States, 34747-1818
Actively Recruiting
5
Central Florida Pulmonary Group, P.A. (CFPG) - Downtown Orlando
Orlando, Florida, United States, 32803-5727
Actively Recruiting
6
Southeastern Research Center
Winston-Salem, North Carolina, United States, 27103-4007
Actively Recruiting
7
University of Oklahoma Health Sciences Center (OUHSC)
Oklahoma City, Oklahoma, United States, 73104-5417
Actively Recruiting
8
Temple University Hospital-Temple Lung Center
Philadelphia, Pennsylvania, United States, 19140
Actively Recruiting
9
Bogan Sleep Consultants, LLC
Columbia, South Carolina, United States, 29201-2953
Actively Recruiting
10
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75235-6243
Actively Recruiting
11
Metroplex Pulmonary and Sleep Center
McKinney, Texas, United States, 75069-1898
Actively Recruiting
12
Research Centers of America
McKinney, Texas, United States, 75071
Actively Recruiting
Research Team
M
Monique Duncan
CONTACT
C
Carol Salter, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here