Actively Recruiting
A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease
Led by Bausch & Lomb Incorporated · Updated on 2026-03-13
423
Participants Needed
32
Research Sites
53 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A 4-Week, Randomized, Double-Masked, Parallel-Group, Active-Controlled, Multicenter Study Evaluating Lifitegrast/Perfluorohexyloctane Fixed-Dose Combination Administered Twice Daily on Signs and Symptoms of Dry Eye Disease
CONDITIONS
Official Title
A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- History of dry eye disease in both eyes for at least 6 months
- Same eye meets dry eye sign criteria at screening and baseline
- Meets dry eye symptom criteria at screening and baseline
- Used non-prescription artificial tears, gels, or lubricants as needed in past 30 days
- Able and willing to follow all study instructions and attend visits
You will not qualify if you...
- Known allergy or sensitivity to any study treatment or its components
- Visual acuity of 20/100 or worse at screening or baseline
- Significant ocular surface abnormalities that may affect study results
- Use of any ocular therapies within 30 days before study
- Unable or unwilling to stop current topical dry eye treatments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 32 locations
1
Eye Doctors of Arizona, PLLC
Phoenix, Arizona, United States, 85028
Actively Recruiting
2
Global Research Management, Inc.
Glendale, California, United States, 91204
Actively Recruiting
3
SoCal Eye - Lakewood Clinic
Long Beach, California, United States, 90805
Actively Recruiting
4
LoBue Laser and Eye Medical Center
Murrieta, California, United States, 92562
Actively Recruiting
5
Eye Research Foundation, Inc.
Newport Beach, California, United States, 92663
Actively Recruiting
6
Wolstan and Goldberg Eye Associates
Torrance, California, United States, 90505
Actively Recruiting
7
Segal Drug Trials/Office of Bruce A Segal, MD
Delray Beach, Florida, United States, 33484
Actively Recruiting
8
Bowden Eye and Associates
Jacksonville, Florida, United States, 32256
Actively Recruiting
9
Shettle Eye Research, Inc
Largo, Florida, United States, 33773
Actively Recruiting
10
Clayton Eye Clinical Research, LLC
Morrow, Georgia, United States, 30260
Actively Recruiting
11
Midwest Cornea Associates LLC
Carmel, Indiana, United States, 46032
Actively Recruiting
12
Kannarr Eye Care, LLC
Pittsburg, Kansas, United States, 66762
Actively Recruiting
13
Vance Thompson Vision - Alexandria
Alexandria, Minnesota, United States, 56308
Actively Recruiting
14
Complete Eye Care of Medina
Medina, Minnesota, United States, 55340
Actively Recruiting
15
Insight Eyecare Specialties, Inc.
Kansas City, Missouri, United States, 64111
Actively Recruiting
16
Moyes Eye Center, P.C.
Kansas City, Missouri, United States, 64154
Actively Recruiting
17
Ophthalmology Consultants, Ltd.
St Louis, Missouri, United States, 63131
Actively Recruiting
18
Comprehensive Eye Care Ltd.
Washington, Missouri, United States, 63090
Actively Recruiting
19
Opthalmic consultants of Long Island
Garden City, New York, United States, 11530
Actively Recruiting
20
Rochester Ophthalmological Group,PC
Rochester, New York, United States, 14618
Actively Recruiting
21
Asheville Eye Associates
Asheville, North Carolina, United States, 28803
Actively Recruiting
22
Oculus Research
Garner, North Carolina, United States, 27529
Actively Recruiting
23
CORE Inc.
Shelby, North Carolina, United States, 28150
Actively Recruiting
24
Vance Thompson Vision - Fargo, ND
West Fargo, North Dakota, United States, 58078
Actively Recruiting
25
Insight Research Clinic LLC.
Powell, Ohio, United States, 43065
Actively Recruiting
26
Scott & Christie Eyecare Associates - The Surgery Center at Cranberry
Cranberry Township, Pennsylvania, United States, 16066
Actively Recruiting
27
West Bay Eye Associates
Warwick, Rhode Island, United States, 02888
Actively Recruiting
28
Southern College of Optometry
Memphis, Tennessee, United States, 38104
Actively Recruiting
29
Total Eye Care PA
Memphis, Tennessee, United States, 38119
Actively Recruiting
30
Advancing Vision Research, LLC
Smyrna, Tennessee, United States, 37167
Actively Recruiting
31
Intouch Clinical Research Center
Houston, Texas, United States, 77034
Actively Recruiting
32
Lake Travis Eye and Laser Center
Lakeway, Texas, United States, 78738
Actively Recruiting
Research Team
S
Study Manager Bausch and Lomb
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
6
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