Actively Recruiting
A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Offspring
Led by Royal Brompton & Harefield NHS Foundation Trust · Updated on 2025-10-01
60
Participants Needed
1
Research Sites
150 weeks
Total Duration
On this page
Sponsors
R
Royal Brompton & Harefield NHS Foundation Trust
Lead Sponsor
C
Cystic Fibrosis Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this study, investigators aim to study in detail the physical (including nutritional and pulmonary) and mental health of females with cystic fibrosis (CF) planning a pregnancy, during pregnancy, and in the early parenthood period. Additionally the health of offspring in infancy and early life will be studied to understand if further screening investigations or clinical care models should be part of clinical guidelines
CONDITIONS
Official Title
A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Offspring
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written informed consent obtained from participant or legal guardian.
- Under care of Royal Brompton Hospital CF Reproductive and Maternal Health Service or Adult CF Service.
- For 'Mama': females aged 16 years or older with confirmed CF, planning pregnancy or pregnant.
- For 'Mini': infants less than 12 months old with one biological parent diagnosed with CF.
- For 'Midi': children aged 3 to 6 years with one biological parent diagnosed with CF.
- Ability to attend required visits and complete investigations.
You will not qualify if you...
- For 'Mama': any significant health condition preventing protocol compliance as judged by investigator.
- History of lung transplantation.
- For 'Mini': legal guardian unable to provide consent.
- Mother has significant non-CF comorbidities affecting infant outcomes as judged by investigator.
- For 'Midi': legal guardian unable to provide consent.
- Significant health condition known to affect lung function or imaging as judged by investigator.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Royal Brompton Hospital
London, United Kingdom
Actively Recruiting
Research Team
A
Amy Downes
CONTACT
I
Idan Bokobza
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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