Actively Recruiting
Study of Brain Activity Changes in Adults Aged 18 to 30 Undergoing ACL Reconstruction Using Neuromotor Training
Led by Stefano Zaffagnini · Updated on 2026-02-27
12
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Lower limb injuries, especially anterior cruciate ligament ACL injuries, are common and often have serious consequences for athletes. These injuries carry a high risk of re-injury and early knee osteoarthritis. The study focuses on how brain activity relates to movement patterns after ACL reconstruction and explores whether neuromotor training can improve these brain patterns to reduce injury risk. Participants will undergo a targeted neuromotor training program designed to improve biomechanical and neuromuscular control. The study will measure brain activation using functional magnetic resonance imaging fMRI before training begins and after it is completed. This approach aims to see if neuromotor training can reduce neural compensations in brain areas linked to movement, supporting a safer return to sport. During the study, patients will have fMRI scans and movement quality assessments over a period of 6 to 9 months. Researchers will analyze changes in brain activity, movement biomechanics, ground reaction forces, and functional brain connectivity. Safety will be monitored by tracking any adverse events. The studys findings may help develop better rehabilitation protocols to lower the chance of ACL re-injury.
CONDITIONS
Brief Title
Study of Functional Magnetic Resonance Signal Variations in Patients Undergoing Anterior Cruciate Ligament Reconstruction With the Application of a Dedicated Neuromotor Training
Research Team
S
Stefano Zaffagnini
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here