Actively Recruiting
A Study of FZ-AD004 in Patients With Advanced Solid Tumors
Led by Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. · Updated on 2026-01-22
121
Participants Needed
1
Research Sites
233 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is one single group of participants with advanced solid tumors. It is the first time the drug has been used in humans. There will be two parts including Dose Escalation and Dose Expansion to evaluate the safety, tolerability, pharmacokinetics, and clinical activity of FZ-AD004.
CONDITIONS
Official Title
A Study of FZ-AD004 in Patients With Advanced Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to give written informed consent
- Age 18 to 75 years, male or female
- Diagnosed with advanced solid tumors by histology or cytology
- Have measurable lesions defined by RECIST v. 1.1
- Expected survival of at least 12 weeks
- Eastern Cancer Cooperative Group (ECOG) performance status of 0 or 1
- Patients of childbearing potential must agree to use contraception during the study and for 6 months after treatment ends
You will not qualify if you...
- History of other malignant tumors within the past 5 years
- Central nervous system metastasis with clinical symptoms
- Major surgery or severe trauma within 4 weeks before first dose
- Systemic high-dose steroids within 2 weeks before starting study treatment
- History of psychotropic drug abuse, alcohol or drug abuse
- Women who are pregnant or breastfeeding
- Any other condition that makes participation unsuitable according to the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Chest Hospital
Shanghai, China
Actively Recruiting
Research Team
X
Xuejing Cheng
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
1
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