Actively Recruiting

Age: 18Years +
All Genders
NCT07102368

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

Led by Janssen-Cilag G.m.b.H · Updated on 2026-05-13

500

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to characterize participants with Crohn's Disease (CD) and Ulcerative Colitis (UC) treated with Guselkumab in a real-world setting, and to assess the clinical effectiveness (how well the treatment works) in the overall population and in different participant subgroups. Furthermore patient-reported outcomes like fatigue, health-related quality of life (HRQoL), sexuality, work productivity and activity as well as treatment satisfaction will be assessed.

CONDITIONS

Official Title

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible for biologic treatment and starting guselkumab as per approved guidelines
  • Signed informed consent allowing data collection and verification
  • Able and willing to complete patient-reported outcome assessments during the study
Not Eligible

You will not qualify if you...

  • History of more than 4 lines of advanced inflammatory bowel disease therapy
  • Previous exposure to interleukin-23 inhibitors, except ustekinumab
  • Previous colectomy and/or pouch surgery
  • Currently enrolled in an interventional clinical study or another non-interventional Janssen or Johnson & Johnson study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Praxis Fur Gastroenteroligie

Berlin, Germany, 10825

Actively Recruiting

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Research Team

S

Study Contact

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany | DecenTrialz