Actively Recruiting
A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)
Led by Johnson & Johnson Private Limited · Updated on 2026-05-08
100
Participants Needed
10
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the safety and how well guselkumab treatment works (efficacy) in participants with psoriatic arthritis (PsA; a chronic, autoimmune form of arthritis that causes joint inflammation) who had inadequate response to standard therapies.
CONDITIONS
Official Title
A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Definite diagnosis of active psoriatic arthritis according to CASPAR criteria with at least one PsA subset
- Negative for rheumatoid factors
- Inadequate response to standard therapies for at least 3 months at the highest recommended doses, including biologics-na�ve or failed/intolerant to biological treatments
- Meet tuberculosis screening criteria including no history or signs of active TB, negative TB tests within 6 weeks before treatment, and chest X-ray with no active or inactive TB within 3 months
- Medically stable based on physical exam, medical history, vital signs, and ECG
- Negative highly sensitive serum beta-hCG at screening for women of childbearing potential
You will not qualify if you...
- History of latent or active granulomatous infection prior to screening
- Known serious allergy to guselkumab or its ingredients
- Serious infection, hospitalization for infection, or IV antibiotic treatment within 2 months before first treatment
- Known history of malignancy or lymphoproliferative disease
- Received or expected to receive live virus or bacterial vaccines within 3 months before, during, or 6 months after study treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
Cims Hospital
Ahmedabad, India, 380060
Actively Recruiting
2
Post Graduate Institute of Medical Education And Research PGIMER
Chandigarh, India
Actively Recruiting
3
Chennai Meenakshi Multispeciality Hospital
Chennai, India, 600004
Actively Recruiting
4
All India Institute of Medical Sciences 1
Gorakhpur, India, 273008
Actively Recruiting
5
Nizams Institute of Medical Sciences
Hyderabad, India, 500082
Actively Recruiting
6
P. D. Hinduja National Hospital and Research Center
Mumbai, India, 400016
Actively Recruiting
7
All India Institute of Medical Sciences
New Delhi, India, 110029
Actively Recruiting
8
Sir Ganga Ram Hospital
New Delhi, India, 110060
Actively Recruiting
9
All India Institute of Medical Sciences
Patna, India, 801507
Actively Recruiting
10
Jehangir Clinical Development Centre
Pune, India, 4110001
Actively Recruiting
Research Team
S
Study Contact
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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