Actively Recruiting

Age: 18Years +
All Genders
NCT07449234

A Study of Guselkumab After Switching From Ustekinumab in Participants With Moderate to Severe Psoriasis

Led by Janssen-Cilag Ltd. · Updated on 2026-05-08

200

Participants Needed

1

Research Sites

81 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to assess the effectiveness and safety of guselkumab following a switch from ustekinumab or an ustekinumab biosimilar in participants with moderate to severe psoriasis, a chronic inflammatory skin disease characterized by erythematous, scaly plaques that may be associated with pain and pruritus, in routine clinical practice.

CONDITIONS

Official Title

A Study of Guselkumab After Switching From Ustekinumab in Participants With Moderate to Severe Psoriasis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of moderate-to-severe plaque psoriasis requiring systemic treatment
  • Currently treated with ustekinumab (originator or biosimilar) and medically indicated to switch to guselkumab
  • Investigator has decided to start treatment with guselkumab
  • Able and willing to answer patient-reported outcomes (PROs)
  • Signed informed consent form for data collection and verification
Not Eligible

You will not qualify if you...

  • Contraindication or hypersensitivity to guselkumab or any ingredient in its injection solution
  • Pregnancy or breastfeeding
  • Currently enrolled in an interventional study
  • Currently enrolled in an observational study sponsored or managed by a Janssen company

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

LKH-Univ. Klinikum Graz

Graz, Austria, 8036

Actively Recruiting

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Research Team

S

Study Contact

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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A Study of Guselkumab After Switching From Ustekinumab in Participants With Moderate to Severe Psoriasis | DecenTrialz